Medication-Assisted
Treatment (MAT)
in Los Angeles

MAT is the gold standard of care for opioid and alcohol use disorders. At Reign Recovery, FDA-approved medications are used carefully and compassionately — always integrated with behavioral therapy and a comprehensive treatment plan, never as a standalone solution.

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UNDERSTANDING MAT

What Is Medication-Assisted Treatment?

Medication-Assisted Treatment (MAT) is the use of FDA-approved medications, in combination with counseling and behavioral therapies, to treat substance use disorders. MAT addresses the neurological and physiological dimensions of addiction — reducing withdrawal symptoms, managing cravings, and stabilizing brain chemistry — while behavioral therapy addresses the psychological and behavioral dimensions.

The combination is significantly more effective than either approach alone. SAMHSA recognizes MAT as the gold standard of care for opioid use disorder and a clinically validated approach for alcohol use disorder. At Reign Recovery, MAT is always integrated into a comprehensive, individualized treatment plan and supervised by our licensed medical team.

What the Research Says About MAT

The evidence for MAT is overwhelming. NIDA, SAMHSA, the American Society of Addiction Medicine (ASAM), and the Surgeon General of the United States all recommend MAT as the evidence-based standard of care for opioid use disorder. Studies consistently demonstrate that MAT reduces opioid use, reduces overdose deaths, improves treatment retention, reduces criminal activity, and improves social functioning.

The 2016 U.S. Surgeon General's Report on Alcohol, Drugs, and Health stated explicitly that medications for opioid use disorder "reduce the risk of fatal overdoses by approximately 50 percent."

Important: MAT Is Determined by Clinical Assessment

Not every individual in treatment at Reign Recovery will use MAT. Whether MAT is appropriate is determined through a thorough clinical and medical assessment at intake. Our medical team works with each individual to determine whether medication is clinically indicated, which medication is most appropriate, and how it fits into their overall treatment plan. MAT is always a clinical decision — never a default or a requirement.

FDA-APPROVED MEDICATIONS

Medications Used at Reign Recovery

All medications used in our MAT program are FDA-approved and prescribed and supervised by our licensed medical team. The appropriate medication — if any — is determined through a comprehensive clinical assessment at intake based on the individual's specific substance use history, physical health, and treatment goals.

TREATS: OPIOID USE DISORDER · FENTANYL ADDICTION
A partial opioid agonist that reduces withdrawal symptoms and cravings without producing the euphoria associated with opioid misuse. Suboxone combines buprenorphine with naloxone to deter misuse. One of the most well-researched and effective MAT medications available.
Administered as a sublingual film or tablet. Requires induction under medical supervision.
TREATS: OPIOID USE DISORDER · ALCOHOL USE DISORDER
An opioid antagonist that blocks the euphoric effects of opioids and alcohol — removing the reward that drives use. Available as a daily oral tablet or monthly injectable (Vivitrol), which removes the need for daily adherence. Requires full detox from opioids before starting.
Available as daily oral tablet (Revia) or monthly injectable (Vivitrol). No physical dependence risk.
TREATS: ALCOHOL USE DISORDER
Reduces the post-acute withdrawal symptoms and protracted abstinence symptoms that drive relapse in the months following alcohol detox — particularly anxiety, insomnia, and restlessness. Best used after detox is complete and sobriety is established.
Taken as oral tablets three times daily. Most effective when combined with counseling and peer support.
TREATS: ALCOHOL USE DISORDER
Creates a severe adverse reaction when alcohol is consumed, acting as a deterrent to drinking. Most effective when adherence is supported by family, therapeutic community, or supervised administration. Used selectively based on clinical appropriateness.
Daily oral tablet. Requires complete abstinence from alcohol before starting and careful medical supervision.

At Reign Recovery, MAT is never used as a standalone treatment. Every individual on MAT receives individual therapy, group therapy, and a comprehensive treatment plan. Medication is one tool in a full clinical program — not the entire program.

We do not require individuals with diabetes to stop insulin to prove their recovery. Opioid use disorder is a medical condition. For many individuals, long-term MAT is the medically appropriate path to a stable, full life in recovery.

MAT is used because addiction is a neurological disorder. Without medication stabilizing brain chemistry, many individuals cannot engage effectively in therapy or maintain sobriety long enough to benefit from behavioral treatment. MAT makes the hard work possible.

MAT medications are prescribed and supervised by licensed physicians, reduce cravings without producing euphoria, and are used as part of a comprehensive treatment plan. Physical dependence on a medication under medical supervision is fundamentally different from addiction.

FREQUENTLY ASKED QUESTIONS

MAT in Los Angeles — Common Questions

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies to treat substance use disorders. The medications work by stabilizing brain chemistry, reducing withdrawal symptoms, and blocking or reducing the euphoric effects of substances. This neurological stabilization makes it possible for individuals to engage more effectively in therapy, maintain treatment, and build the foundations of lasting recovery.
MAT is considered for individuals with opioid use disorder (including fentanyl and heroin addiction) and alcohol use disorder. Candidacy is determined through a comprehensive medical and clinical assessment at intake. Factors considered include the severity and duration of use, previous treatment history, physical health status, and individual treatment goals. Not everyone in treatment will use MAT — it is a clinical decision made in collaboration with the individual and our medical team.
No. This is a common misconception that the clinical evidence does not support. MAT medications are prescribed and supervised by licensed physicians, used at therapeutic rather than euphoric doses, and implemented as part of a comprehensive treatment plan. Physical dependence on a clinically prescribed medication is fundamentally different from addiction. The goal of MAT is not permanent medication dependence but stable functioning that supports engagement in therapy and life in recovery.
The duration of MAT varies widely based on individual clinical needs and goals. For some individuals, MAT is used for a defined period during early recovery — typically 6 to 12 months — before a supervised taper. For others, long-term or indefinite MAT is the most clinically appropriate path. SAMHSA and ASAM guidelines recognize that there is no universally correct duration and that treatment length should be determined by the individual's clinical response and circumstances, not arbitrary timelines.
Yes. Most major insurance plans cover MAT medications and the associated medical supervision as part of addiction treatment. Federal mental health parity laws require that substance use disorder treatment — including medications — be covered at the same level as other medical conditions. Reign Recovery accepts Blue Cross Blue Shield, Aetna, Cigna, United Healthcare, Anthem, and more. Our admissions team verifies your specific coverage confidentially and at no cost.
Yes — and this is the recommended approach. Research consistently shows that MAT combined with behavioral therapy produces significantly better outcomes than either approach alone. At Reign Recovery, individuals on MAT receive the full residential program including individual therapy, group therapy, CBT and DBT skills training, trauma-informed care, and holistic therapies. MAT is one component of a comprehensive treatment plan — not a substitute for the clinical work of recovery.